Bayesian Gene Heritability Analysis¶
By Viola Fanfani (v.fanfani@sms.ed.ac.uk)
The Bayesian Gene Heritability Analysis software (BAGHERA) estimates the contribution to the heritability of a trait/disease of all the SNPs in the genome (genome-wide heritability) and those nearby protein-coding genes (gene-level heritability).
BAGHERA requires only summary statistics from a Genome-wide Association Study (GWAS), LD scores calculated from a population matching the ethnicity of the GWAS study and a gene annotation file in GTF format.
Workflow¶
Alongside BAGHERA, we are providing a snakemake workflow repository with sample data. workflow-baghera
Getting Started¶
Usage¶
Issues¶
BAGHERA is still under development, and a major refactoring will happen at some point. If you find a bug, please report it on GitHub.